Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
Reactions mass of N-{2-[(4-bromo-6-substituted-2-alkyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)diazenyl]-[alkyl(2-methoxyalkyl)amino]phenyl}acetamide) and N-{2-[(4-bromo-6-substiuted-2-alkyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)diazenyl]-[alkyl(2-hydroxy-3-phenoxypropyl)amino]phenyl}acetamide
EC number: - | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Determination of the Abiotic Degradation of FAT 40858/A TE (Hydrolysis as a Function of pH).
Waiver.
Key value for chemical safety assessment
Additional information
Method :
Testing was not carried out, using a procedure designed to be compatible with Method C7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004, due to the following reasons:
• The test item is a fairly complex mixture; whereas, the test is not appropriate for complex mixtures.
• The water solubility of the test item has been determined to be less than or equal to 2.13 x 10-5 g/L at 20.0 ± 0.5 °C, which is excessively low with respect to hydrolysis testing.
Therefore, as hydrolysis testing needs to be performed at a concentration of less than half of the water solubility (of the least water soluble component) and the analytical methodology needs to have sufficient sensitivity and accuracy to be able to accurately measure the decrease in concentration for each test item component over time, it was concluded that testing would be unfeasible.
A preliminary scientific assessment of the main constituents of the test item indicated that both of these constituents contain at least one potentially hydrolysable functional group.
The hydrolytic stability of the main constituents was estimated using the specialist estimation software, HYDROWIN v2.00 (September 2010), © 2000 U.S. Environmental Protection Agency. The results are presented in Appendix 1.
Results:
Using HYDROWIN v2.00 (September 2010), © 2000 U.S. Environmental Protection Agency, the main constituents of the test item were considered to be stable towards hydrolysis at pH 4, 7 and 9. 3.7.3
Conclusion:
Overall, it was concluded that the test item would be essentially stable towards hydrolysis at pH 4, 7 and 9.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
