Di-mu-chloro-bis(hapto-1,5-cyclooctadiene)dirhodium(I)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP compliant, guideline study, available as an unpublished report, acceptable without restrictions.

Qualifier:

equivalent or similar to guideline

Guideline:

other: Method A6 Water Solubility and OECD Method 105

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Water solubility:

1.56 g/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

>= 3.4 - <= 3.9

Details on results:

On completion of the standard water solubility test an increasing trend of resulting solubility versus initial saturation period was obtained indicating that a saturation plateau had not been achieved. Subsequently additional extended saturation period samples were prepared. the additional experimental step of testing (protected from light) was also applied to these extra flasks to eliminate photolysis and the accumulation of a soluble rhodium containing degradation product as being the mechanism for the increase in apparent solubility observed.
Although with protection from light a moderate reduction in final solubility was obtained for the repeat 72 hour saturation /24 hour equilibration sample, it was evident that saturation had been satisfactory achieved by the use of a 96hr saturation period.

The water solubility of the test item has been determined to be 0.649 g/L of solution at 20.0 ± 0.5 °C monitoring the rhodium concentration of the sample solutions; equivalent to a di-μ-chloro-bis(hapto-1,5-cyclooctadiene)dirhodium(I) solubility of 1.56 g/L of solution at 20.0 ± 0.5 °C.

Conclusions:

The water solubility of the test item has been determined to be 0.649 g/L of solution at 20.0 ± 0.5 °C monitoring the rhodium concentration of the sample solutions; equivalent to a di-μ-chloro-bis(hapto-1,5-cyclooctadiene)dirhodium(I) solubility of 1.56 g/L of solution at 20.0 ± 0.5 °C.

Executive summary:

This is a GLP compliant, guideline study considered suitable for use as the key study for this endpoint. The water solubility of the test item has been determined to be 0.649 g/L of solution at 20.0 ± 0.5 °C monitoring the rhodium concentration of the sample solutions; equivalent to a di-μ-chloro-bis(hapto-1,5-cyclooctadiene)dirhodium(I) solubility of 1.56 g/L of solution at 20.0 ± 0.5 °C.

Description of key information

The water solubility of the test item has been determined to be 0.649 g/L of solution at 20.0 ± 0.5 °C monitoring the rhodium concentration of the sample solutions; equivalent to a di-μ-chloro-bis(hapto-1,5-cyclooctadiene)dirhodium(I) solubility of 1.56 g/L of solution at 20.0 ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:

1.56 g/L

at the temperature of:

20 °C

Additional information

O'Connor and Woolley (2011) is a GLP compliant study following OECD TG 105 and is considered suitable for use as the key study for this endpoint. The water solubility of the test item has been determined to be 0.649 g/L of solution at 20.0 ± 0.5 °C monitoring the rhodium concentration of the sample solutions; equivalent to a di-μ-chloro-bis(hapto-1,5-cyclooctadiene)dirhodium(I) solubility of 1.56 g/L of solution at 20.0 ± 0.5 °C.