Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Version / remarks:
UN Recommendations on the Transport of Dangerous Goods
Deviations:
no
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl acetate
EC Number:
611-880-6
Cas Number:
5976-55-6
Molecular formula:
C21H28O3
IUPAC Name:
(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl acetate
Test material form:
solid: crystalline
Details on test material:
Test item: estradiol-methyl-ether-acetateCAS No.: 5976-55-6Physical state: white crystalline powderStorage:15-30 °C, protected from light and wet

Results and discussion

Flammable solidsopen allclose all
Test procedure:
burning rate test: preliminary screening test
Remarks on result:
other: non-flammable
Test procedure:
burning time (test type not further specified)
Remarks on result:
other: Burning rate time was not performed because of the result of the preliminary test.
Pyrophoric solids
Test procedure:
ignition time on contact with air
Remarks on result:
no ignition on contact with air (not further specified)
Remarks:
According to manufacturing/handling experiences.
Substances / mixtures which in contact with water emit flammable gases
Remarks on result:
no reaction with water observed
Remarks:
According to company laboratory instructions.

Any other information on results incl. tables

In the vicinity of the heat source the solid surface is melted and smoke. The entire melted surface was not burned.

Applicant's summary and conclusion

Interpretation of results:
non flammable
Conclusions:
The substance (estradiol-methyl-ether-acetate) should not be considered as flammable and no further testing is required. According to the GHS criteria the measured substance cannot be classified.