Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-11-14 to 2011-11-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2011

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
, 2006
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
, 2008
Deviations:
no
GLP compliance:
yes (incl. certificate)
Remarks:
, signed 2010-08-25
Type of method:
effusion method: vapour pressure balance

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
- Physical state: solid, whitish to white crystals
- Storage condition of test material: ambient temperature, dark, dry, in original container

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
0 Pa
Remarks on result:
other: calculated by extrapolation of the measured vapour pressure
Temp.:
25 °C
Vapour pressure:
0 Pa
Remarks on result:
other: calculated by extrapolation of the measured vapour pressure
Temp.:
50 °C
Vapour pressure:
0 Pa
Remarks on result:
other: calculated by extrapolation of the measured vapour pressure

Any other information on results incl. tables

Results of the Effusion method

No.

Temperature / °C

Vapour pressure / Pa

1

78

1.86 ×10-4

2

98

1.87 ×10-3

3

108

6.56 ×10-3

4

118

2.44 ×10-2

5

128

7.79 ×10-2

6

138

2.25 ×10-1

7

148

1.00 ×10-0

8

158

2.33 ×10-0

The vapour pressure at 158 °C is already slightly above the upper limit of the vapour pressure balance, but due to the limited abbreviation from the limit and the very good fit to the regression, this value can also be used for the evaluation of the data.

From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation (log10p = A + (B/T)) can be derived by regression of the data points to A = 18.6632 and B = -7912.43. The vapour pressure values for the temperatures 20, 25 and 50 °C were calculated.

Applicant's summary and conclusion

Conclusions:
According to OECD Guideline 104 (2006) and Regulation (EC) No 440/2008 Method A.4, the vapour pressure of the substance was calculated by extrapolation of the measured vapour pressure curve for the following temperatures:
20 °C: 4.7 ×10-9 Pa
25 °C: 1.3 ×10-8 Pa
50 °C: 1.5 ×10-6 Pa