Registration Dossier
Registration Dossier
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EC number: 700-488-1 | CAS number: 873888-84-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (4Z)-hept-4-en-2-yl salicylate
- EC Number:
- 700-488-1
- Cas Number:
- 873888-84-7
- Molecular formula:
- C14H18O3
- IUPAC Name:
- (4Z)-hept-4-en-2-yl salicylate
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 49 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 67
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
The ready biodegradability of the test item was determined by the manometric respirometry test.
The test item undergoes 67% of biodegradation after 28 days (71% after 49 days) in the test conditions. The 10 -day window criterion is not fulfilled (22% biodegradation on day 4 and 54% on day 14).
This should be attributed to the structure of the test substance: esters are usually not viewed as a single substance by microorganisms. Both hydrolysis products are sequentially degraded, often by different microorganisms. Both hydrolysis products are sequentially degraded, often by different microorganisms. The 10 -day window criterion should therefore not used as a pass fail criterion.
The curve obtained with the reference substance alone and with GR-86 -3792 + reference substance shows no toxic effect of the test item to the microorganisms at the test concentration.
Thus, te test item should be regarded as readily biodegradable according to this test.
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