Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-302-7 | CAS number: 80-70-6
Phototransformation in air
Administrative data
Link to relevant study record(s)
Description of key information
After evaporation or exposure to the air, the substance will be rapidly degraded by photochemical processes.
Key value for chemical safety assessment
- Half-life in air:
- 2.8 h
- Degradation rate constant with OH radicals:
- 0 cm³ molecule-1 s-1
Additional information
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) (Q)SAR results were used forphototransformationin air. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on phototransformationin air are not provided.
Assessment
Based on an estimated OH radical rate constant of 137.059E-12 cm³/(molecule*sec), the half-life of 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) was calculated to be 2.8 h (test conditions: sensitizer for indirect photolysis: OH; 0.5 E06 OH/cm³, 24-h day) (BASF SE, 2018). The substances were within the applicability domain of the model; however, as the substance is a tertiary amine, the estimate may be highly uncertain (AOPWIN v1.92, EPI Suite v4.11, BASF SE, 2018). Therefore, after evaporation or exposure to the air, the product will be rapidly degraded by photochemical processes.
Therefore, after evaporation or exposure to the air 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) will be rapidly degraded by photochemical processes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
