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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation in aquatic species: fish
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Description of key information

Waiver:
The performance of a test for bioaccumulation in aquatic species, preferably fish, is scientifically unjustified.
REACh Regulation No. 1907/2006, Annex IX, Sect. 9.3.2, Col. 2, states as follows:
“9.3.2 The study need not be conducted if:
 - the substance has a low potential for bioaccumulation (for instance a log Kow <= 3) and/or a low potential to cross biological membranes, or
 - direct and indirect exposure of the aquatic environment is unlikely.”
The bioaccumulation factors (BCF) were calculated to be 3.348 L/kg or log BCF 0.525 (Monomer), 274.3 L/kg or log BCF 2.438 (dimer) and 3.399 L/kg or log BCF 0.531 (MIBK). Furthermore the substance is readily biodegradable. The log Pow values of 2 out of 3 constituents of this multi-constituent substance (monomer=1.3, MIBK=1.31) are well below the threshold of 3 as given in REACH Annex IX. Only the experimental log Pow value of the dimer (4.2) is above the threshold value of 3 but is still below the threshold value of 4.5 defining B-substances described in REACH Regulation No. 1907/2006, Annex XIII and in the guidance document (Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.11: PBT/vPvB). Based on the properties of organic peroxides the substance can be expected to hydrolyse rapidly. Due to these results the test substance was considered to have no bioaccumulation potential and to have low potential to cross biological membranes. Thus, a test for bioaccumulation of the test substance in the aquatic compartment is scientifically unjustified.

Key value for chemical safety assessment

Additional information