Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:
Migrated from Short description of key information:
In one reliable skin sensitisation study (guinea-pig maximisation test; DCC, 1995) conducted to OECD 406, trimethoxysilane was negative for skin sensitisation.

Respiratory sensitisation

Endpoint conclusion
Additional information:

Only one reliability score 1 study is available for trimethoxysilane; this is the key study for this endpoint.


Migrated from Short description of key information:
There are no data for respiratory sensitisation.

Justification for classification or non-classification

The available data do not suggest that trimethoxysilane should be classified as a skin sensitiser.