Registration Dossier
Registration Dossier
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EC number: 225-716-2 | CAS number: 5026-74-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No acute toxicity to aquatic invertebrates testing data is available for the p-isomer therefore a read across approach has been utilised to fulfill this endpoint.
Determination of the acute short-term toxicity of m-(2,3 -epoxypropoxy)-N,N-bis(2,3 -epoxypropyl)aniline in Daphnia magna. For further details of the read across please see document enclosed in Chapter 13.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 18 mg/L
Additional information
In the key study experiment, a 48 -h acute toxicity study, water fleas (Daphnia magna) were exposed to m-(2,3-epoxypropoxy)-N,N-bis(2,3 -epoxypropyl)aniline under static conditions at the following nominal concentrations (final test): (blank-control), 0.10, 0.32, 1.0, 3.2, 10, 32 and 100% of the water soluble fraction prepared at 100 mg/L. The test substance did not induce significant acute immobilisation of Daphnia magna at 10 mg/L after 48 hours of exposure based on analytically confirmed nominal exposure concentrations. The 48h-EC50 was 18 mg/L based on analytically confirmed nominal exposure concentrations (95% confidence interval between 10 and 32 mg/L) The study is reliable without restrictions.
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