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Physical & Chemical properties

Partition coefficient

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Description of key information

log Pow - calculated using KOWWIN v1.68 (weight-averaged value): 4.62 
log Pow - calculated from weight-averaged log Koc value: 4.69
log Pow - calculated using KOWWIN v1.67 (individual constituents): 2.03 - 5.26
log Pow - HPLC method: 5.01-5.82

Key value for chemical safety assessment

Log Kow (Log Pow):
4.66
at the temperature of:
25 °C

Additional information

The key value for chemical safety assessment is derived in a weight-of-evidence approach from the two calculated log Pow values (average of values: 4.69 and 4.62) for the substance Alcohols, C12-13, ethoxylated, < 2.5 EO (CAS No. 66455-14 -9).

 

Two types of calculations were applied:

1. based on weight-averaged log Koc values using the TGD equation for predominantly hydrophobic substances: log Koc = 0.81 log Pow + 0.10 thus log Pow = (log Koc – 0.10)/0.81) (2003 EU Technical Guidance Document on Risk Assessment Part III, Chapter 4, Section 4.3 (pp 24 – 27)

2. based on EPIsuite v 4.10, KOWWIN v 1.68 log Pow values for (possible) individual constituents of the substance; a weighting based on normalized composition was applied to derive a log Pow value for the whole substance.

 

Other available KOWWIN v1.67 calculations (log Pow =2.03 - 5.26) for individual components of the substance were not taken to averaging since the values log Pow < 4 refer to the estimations for higher ethoxylated alcohols nEO = 10.