Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-081-7 | CAS number: 78-08-0
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- exposure considerations
- Justification for data waiving:
- other:
Reference
Description of key information
A long-term toxicity study on fish is not necessary as
- exposure considerations in accordance with Annex XI, Section 3, indicate that exposure of aquatic organisms to triethoxy(vinyl)silane is absent or not significant
and
- the substance has a low hazard potential based on the available toxicity data.
Key value for chemical safety assessment
Additional information
In accordance with Annex XI, Section 3, exposure of aquatic organisms to triethoxy(vinyl)silane (CAS No. 78-08-0), is absent or not significant.
The environmental hazard assessment, PNEC derivation and risk characterization is based on the silanol hydrolysis product, vinylsilanetriol, as the substance hydrolyses rapidly. The other hydrolysis product, ethanol, is known for its absence of environmental toxicity. Since no aquatic toxicity data is available for the parent compound or its silanol hydrolysis product, good quality data was read-across from a structural analogue substance trimethoxy(vinyl)silane (CAS No. 2768-02-7). The source substance hydrolyses rapidly under environmental conditions (DT50 = 0.1 h at pH 7 and 20-25 °C) to form the common silanol hydrolysis product vinylsilanetriol and the non-common alcohol hydrolysis product methanol. The alcohol hydrolysis product of the source substance is negligible for the hazard assessment as no effects occur for this substance up to the concentrations tested in the studies.
The hazard assessment showed no short-term aquatic hazard to all three trophic levels (all acute effect values > 100 mg/L). Additionally, a chronic toxicity study on aquatic invertebrates is available, which showed moderate long-term toxicity with an obtained 21-day NOEC of 28.1 mg/L, equivalent to 20 mg/L vinylsilanetriol. Consequently, the 21-day NOEC of 20 mg/L obtained in the study on aquatic invertebrates was used for PNECs derivation as outlined in chapter 6. The silanol hydrolysis product is very well soluble. Significant deviations from this overall ecotoxicity profile are not expected and greater long-term toxicity in an additional test with fish is considered unlikely.
The risk characterization for the silanol hydrolysis product of the substance indicated no risk to the aquatic environment (RCR < 1). For detailed information on the risk assessment please refer to the attached documentation in Section 13.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
