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EC number: 202-319-2
CAS number: 94-28-0
TABLE STILL TO BE ADDED APPENDIXES REQUIRED
Four groups of 10 male CRI:CD(SD)IGS BR rats were exposed to aerosol
atmospheres (1.9-2.4 µm) of 3G0 at 0 (control), 10+0.35,300+5.8
or 1000+19 mg/m3(mean+S.E.M.). Animals were
exposed nose only, 6 hours a day for a total of 9 exposures over a
2-week period. The dosing period was followed by a recovery period in
half of the animals No test substance related effects were observed in
clinical observations, body weights, clinical pathology, gross necropsy
observations and microscopic pathology.Based
upon the observation of no significant effects following exposure to
3G0, the no observed- Adverse effect level (NOAEL) for a 2-week repeated
inhalation exposure was 1000 mg/m3for male rats.
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