Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Remarks:
no analytical monitoring of test concentrations
Qualifier:
according to guideline
Guideline:
other: German standard DIN 38412 Part 9
GLP compliance:
no
Analytical monitoring:
no
Details on sampling:
not specified
Vehicle:
not specified
Details on test solutions:
not specified
Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Details on test organisms:
TEST ORGANISM
- Strain: SAG 86.81
- Source: Algensammlung Goettingen

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Post exposure observation period:
not specified
Hardness:
not specified
Test temperature:
23.3 °C
pH:
not specified
Salinity:
not applicable
Conductivity:
not specified
Nominal and measured concentrations:
Nominal test concentration (mg/L): 25, 50, 100, 250, 500, control; measured values not available
Details on test conditions:
TEST SYSTEM
- No. of vessels per concentration: 4
- No. of vessels per control: 4

EFFECT PARAMETERS MEASURED :
- Determination of cell concentrations: fluorimeter


Reference substance (positive control):
yes
Remarks:
Potassium dichromate
Key result
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
76 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 500 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Reported statistics and error estimates:
Tallarida, R .J . Jacob . L .S . (1979) : The Dose-Response Relation in Pharmacology S. 98 - 103 Springer-Verlag

EbC10 (96h) = 83 mg/L,
EbC50 (96h) > 500 mg/L

Description of key information

Key value is based on effect concentrations related to inhibition of growth rate of freshwater algae.

Key value for chemical safety assessment

EC50 for freshwater algae:
500 mg/L
EC10 or NOEC for freshwater algae:
76 mg/L

Additional information

The short-term toxicity of 1,4 -Butanediol to algae has been studied according to several guideline methods under GLP and non-GLP conditions. These studies have yielded EC50 values of >500 mg/L and >1000 mg/L, and an EC10 value of >76 mg/L. These data indicate that 1,4-Butanediol exhibits a low order of toxicity to aquatic algae.