Registration Dossier
Registration Dossier
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EC number: 203-786-5 | CAS number: 110-63-4
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data from reliable source, Ministry of International Trade and Industry (MITI) / Ministry of Economy, Trade, and Industry (METI) - Japan
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Butane-1,4-diol
- EC Number:
- 203-786-5
- EC Name:
- Butane-1,4-diol
- Cas Number:
- 110-63-4
- Molecular formula:
- C4H10O2
- IUPAC Name:
- butane-1,4-diol
Constituent 1
- Specific details on test material used for the study:
- purity: 99.5 %
- Radiolabelling:
- not specified
Study design
- Analytical monitoring:
- not specified
- Details on sampling:
- not specified
- Buffers:
- pH 4, 7, 9
- Details on test conditions:
- Temperature: 25 °C
biotic (sediment)
- Positive controls:
- not specified
- Negative controls:
- not specified
Results and discussion
- Preliminary study:
- not specified
- Test performance:
- not specified
- Transformation products:
- no
Total recovery of test substance (in %)open allclose all
- % Recovery:
- 100
- pH:
- 4
- Temp.:
- 25 °C
- % Recovery:
- 100
- pH:
- 7
- Temp.:
- 25 °C
- % Recovery:
- 100
- pH:
- 9
- Temp.:
- 25 °C
Dissipation DT50 of parent compoundopen allclose all
- Key result
- pH:
- 4
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 h-1
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 h-1
- Key result
- pH:
- 9
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 h-1
- Other kinetic parameters:
- Half life: Stable at pH 4, 7, 9 at 25 °C
- Details on results:
- not specified
- Results with reference substance:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Hydrolytically stable at pH 4, 7, 9 at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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