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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The substance is acutely not harmful to aquatic organisms.

Additional information

Table: Overview of aquatic toxicity data available for the substance:

 

Test organism

Test guideline

Endpoint

Value

Resource

Short-term toxicity to fish

 

Experimental data

 

 

 

 

 

 

 

 Lepomis macrochirus

 

ASTM, 1980

96-h LC50

 

> 10000 mg/L (nom)

 

Key study; Dawson, 1975

 

 

Pimephales promelas

Standard Methods for the Examination of Water and Wastewater, 15th ed.

 

96-h LC50

70200 mg/L (nom. an. ver.)

 

Supporting study; Geiger, 1988

 

Estimated data

 

 

 

 

 

 

 

-

ECOSAR calculation

96-h LC50

 

286839 mg/L

 

Supporting study; QSAR

 

Long-term toxicity to fish

 

Experimental data

 

 

 

 

 

 

 

Menidia pe.

 

ASTM E-47.01

 

28 -d NOEC

 

> 40 mg/L (meas.)

 

Key study Montgomery, 1985

 

Estimated data

 

 

 

 

 

 

 

 

ECOSAR calculation

 

 ChV

 

18640 mg/L

 

Supporting study, QSAR

 

Short-term toxicity to aquatic invertebrates

Experimental data

 

 

 

 

 

 

 

Daphnia magna

EPS 1/RM/11 (EC 1990/1996)

 

48-h EC50

 

62630 mg/L (nom. an. ver.)

 

Key study, RA to CAS 111-46-6; PTAC, 2006

 

 

Hyalella azteca

 

EPS 1/RM/33 (EC 1997)

 

96-h LC50

 

65980 mg/L (nom. an. ver.)

 

Key study; RA to CAS 111-46-6, PTAC, 2006

 

 

Daphnia magna

 

OECD 202

 

48-h EC50

 

> 100 mg/L

 

Key study; RA to CAS 107-21-1, BASF AG, 1998

 

Hyalella azteca

 

EPS 1/RM/33 (EC 1997)

 

96-h LC50

 

43500 mg/L (nom. an. ver.)

 

Supporting study; PTAC, 2006

 

Estimated data

 

 

 

 

 

 

 

-

 

ECOSAR calculation

 

48-h EC50

 

115220 mg/L

 

Supporting study; QSAR

 

Long-term toxicity to aquatic invertebrates

 

Experimental data

 

 

 

 

 

 

Americamysis bahia

 

ASTM E-47.01, Draft No. 2, 1982

 

23-d NOEC

 

>= 1000 mg/L (meas.)

 

Key study; Montgomery et al., 1985

 

 

Daphnia magna

 

ASTM 47.01, Draft No. 1

 

21-d NOEC

 

>15000 mg/L

 

Key study; Adams & Heidolph, 1985

 

 

 Daphnia magna

 

Reproduction test with the waterflea Daphnia magna under standardised test conditions

21-d NOEC

 

> 6160 mg/L

 

Supporting study; LeBlanc & Surprenant, 1983

 

Estimated data

 

 

 

 

 

 

 

-

 

ECOSAR calculation

 

16-d ChV

4288 mg/L

 

Supporting study; QSAR

 

Toxicity to aquatic algae and cyanobacteria

 

Experimental data

 

 

 

 

 

 

Raphidocelis subcapitata

 

OECD 201

 

72h NOEC

 

> 100 mg/L

 

Key study; RA to CAS 4792-15-8; Mead, 2003

 

 

Raphidocelis subcapitata

 

EPA 600/9-78-018

96-h ErC50

 

6500 – 13000 mg/L

 

Supporting study; RA to CAS 107-21-1 DOW, 1982

 

Estimated data

 

 

 

 

 

 

 

-

 

ECOSAR calculation

 

96-h ErC50 ChV

 

 

20518 mg/L

2486 mg/L

 

Supporting study; QSAR

 

Toxicity to microorganisms

 

 

activated sludge, domestic

 

ISO 8192

 

30-min EC20

 

>1995 mg/L

 

Key study; RA to CAS 111-46-6; BASF AG, 1982

 

 

activated sludge, domestic

 

OECD 209

 

3-h EC50

 

>1000 mg/L

 

Supporting study; RA to CAS 111-46-6, Klecka, 1985