Registration Dossier
Registration Dossier
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EC number: 202-966-0 | CAS number: 101-68-8
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other: review
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Falling short of highest standards concerning aspects of protocol or reporting. Very well documented peer reviewed review.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicological review of methylene diphenyl diisocyanate (MDI) (CAS No. 101-68-8 and 9016-87-9): in support of summary information on the Integrated Risk Information System (IRIS)
- Author:
- USEPA
- Year:
- 1 998
- Bibliographic source:
- US Environmental Protection Agency
Materials and methods
- Type of study / information:
- Type: other: carcinogenicity assessment (inhalation chronic toxicity and carcinogenicity assessment: IRIS)
Test material
- Reference substance name:
- 4,4'-methylenediphenyl diisocyanate
- EC Number:
- 202-966-0
- EC Name:
- 4,4'-methylenediphenyl diisocyanate
- Cas Number:
- 101-68-8
- Molecular formula:
- C15H10N2O2
- IUPAC Name:
- 1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene
- Reference substance name:
- benzene, 1,1'- methylenebis[4-isocyanato-
- IUPAC Name:
- benzene, 1,1'- methylenebis[4-isocyanato-
- Details on test material:
- diphenylmethane diisocyanate : casnr. 101-68-8 and 9016-87-9
Constituent 1
Constituent 2
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
