Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

A 96-hour LC50 value of 271 mg/l (measured concentration) has been determined for the effects of trimethylsilanol on mortality of Oncorhynchus mykiss.
A 96-hour LC50 value of 0.083 mg/l unionised NH3/l (measured concentration) has been determined for the effects of ammonia on mortality of Oncorhynchus gorbusha.

Key value for chemical safety assessment

Additional information

A reliable acute toxicity test result for hexamethyldisilazane is available for freshwater fish (Brachydanio rerio) : 96 h LC50 of 88 mg/l. It is likely that the test organisms were exposed to the hydrolysis products of the substance.

A reliable short-term aquatic toxicity test result is available for the test substance silanol hydrolysis product, trimethylsilanol (CAS 1066-40-6). A 96-hour LC50 value of 271 mg/l (measured concentration) has been determined for the effects of trimethylsilanol on mortality of Oncorhynchus mykiss.

Reliable short-term test results are available for ammonia sourced from the Environment Agency Proposed EQS for Water Framework Directive Annex VIII Substances: Ammonia (un-ionised) 2007. The most sensitive species to ammonia was found to be fish (Oncorhynchus gorbusha- pink salmon), with an LC50 of 0.083 mg un-ionised NH3/L (Rice and Bailey, 1980).