Registration Dossier
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EC number: 253-575-7 | CAS number: 37640-57-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The substance as well as the decomposition products melamine and cyanuric acid are hydrolytically stable in the aqueous environment.
Key value for chemical safety assessment
Additional information
The substance has not been tested as a study is scientifically not justified.
The substance is a high molecular weight complex, self-assembled via organized network of hydrogen bonds and aromatic ring stacking. The molecules of melamine and cyanuric acid are strongly bound in the crystal lattice and require considerable energy to remove them. The absence of a melting point, the high decomposition temperature and the poor solubility in any solvent is a consequence of this complexation behaviour. The substance is only defined through the solid state. In such a case, water solubility is the composition of the aqueous solution formed at equilibrium under a defined set of conditions. Due to the measurement of solubility, the composition consists of dissolved melamine and dissolved cyanuric acid. Thus, under environmental conditions and at predicted concentrations in the aqueous environment, the substance is expected to dissociate into the two components melamine and cyanuric acid. Therefore read-across it is justified from the supporting substances melamine or cyanuric acid.
For the component 108-80-5 (cyanuric acid):
The substance is hydrolytically stable.
For the component 108 -78 -1(melamine):
Melamine is hydrolyzed by mineral acid or inorganic alkali. Hydrolysis proceeds stepwise, with loss of one, two, or all three amino groups, i.e. producing ammeline, ammelide and cyanuric acid. The product spectrum varies with temperature, pH, and concentration; the final product is cyanuric acid [108-80-5]. However, there is no indication that the substance hydrolyses under conditions defined by testing guidelines.
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