Registration Dossier
Registration Dossier
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EC number: 202-327-6 | CAS number: 94-36-0
Toxicity to other above-ground organisms
Administrative data
- Endpoint:
- toxicity to other above-ground organisms
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Embryotoxic Effects of Eight Organic, Peroxides and Hydrogen Peroxide on Three-Day Chicken Embryos
- Author:
- Korhonen, A., Hemminki, K. and Vainio, H.
- Year:
- 1 984
- Bibliographic source:
- Environ. Res., 33, 54 ~ 61.
Materials and methods
- Principles of method if other than guideline:
- Method: other: Embrytoxic effect
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Dibenzoyl peroxide
- EC Number:
- 202-327-6
- EC Name:
- Dibenzoyl peroxide
- Cas Number:
- 94-36-0
- Molecular formula:
- C14H10O4
- IUPAC Name:
- diphenylperoxyanhydride
Constituent 1
Test organisms
- Test organisms (species):
- other: Chicken Embryo
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Effect conc.:
- 0.99 other: µmoles/egg
- Basis for effect:
- other: Embryotoxic effect
Any other information on results incl. tables
RS-Freetext:
EC50 = 0.24
LD50 = 0.82
Applicant's summary and conclusion
- Executive summary:
Embryotoxic effect of benzoyl peroxide to three-day chicken
egg was tested. Acetone was used as solvent for benzoyl
peroxide and the solution volume of 5 µl was injected into
shell membrane in the air chamber of the egg during 14 days.
The eggs were incubated. Malformations, like defects of the
right eye of the embroys, were observed.
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