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EC number: 256-032-2
CAS number: 42978-66-5
The inhibition of the degradation activity
of activated sludge is not anticipated when TPGDA introduced in
appropriate low concentrations.
For assessment of ecotoxicity of
Tripropylenglykoldiacrylate (TPGDA, CAS 42978-66-5) to aquatic
microorganisms a weight-of-evidence approach was used. This approach
consists of three available experimental studies.
In a short-term respiration test a 30 -min
EC10 of > 10000 mg/L were determined, using the Pseudomonas putida
species as inoculum. Hence, the30 -min EC50 is also >10000 mg/L (BASF
AG, 1988, rep no.: 01/88/0671).
In a GLP guideline study conducted
according to OECD 209 the structurally similar substance CAS 57472-68-1
was tested with domestic activated sludge. In this study a 30-min EC20
was determined to be > 1000 mg/L (BASF AG, rep no.: 02/0368/08/1, 2002).
Tripropylenglykoldiacrylate (TPGDA, CAS 42978-66-5) was tested in a
Warbung-Test, DEV/L2. Activated sludge was used as a test organism in
this study. The 30-min EC20 was determined to be > 1000 mg/L. However,
this study is poor documented and, therefore, not reliable for the
Overall it can be considered, that the
lowest ECx value is higher than 1000 mg/L. Thereofore, this value was
used as a worst-case for the derivation of the PNECs STP.
Therefore, based on the
weight-of-evidence approach, it can be concluded, that the inhibition of
the degradation activity of activated sludge is not anticipated when
introduced in appropriate low concentrations.
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