Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-064-4 | CAS number: 77-86-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50(48h) > 980 mg/L for Daphnia magna (OECD 202)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 980 mg/L
Additional information
There is one short-term aquatic invertebrate study available for 2-amino-2-(hydroxymethyl)-1,3-propanediol (TRIS AMINO), which was used as key study for the assessment. The study was conducted according the OECD guideline 202 and GLP (Urann, 2011). The test organism Daphnia magna was exposed to TRIS AMINO in a static system for 48 hours, at the measured test concentrations 63, 130, 260, 520, 980 mg a.i./L. Except for a 15% immobilisation at the highest test concentration, no effects were observed. The EC50 value was thus estimated to be > 980 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
