Registration Dossier
Registration Dossier
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EC number: 200-240-8 | CAS number: 55-63-0
Endpoint summary
Administrative data
Description of key information
The GTN is GTN is harmful.
Tests skin irritation was made on rabits in vivo.
Tests eye irritation was made on rabits in vivo.
Undiluted nitroglycerin is a 'sensitive' high explosive and the danger of a major explosion of TNG vapors or mist in an inhalation study, with resulting major damage to personnel and facility, is too great to consider undertaking such a toxicological study
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Undiluted nitroglycerin is a 'sensitive' high explosive and the danger of a major explosion of TNG vapors or mist in an inhalation study, with resulting major damage to personnel and facility, is too great to consider undertaking such a toxicological study
Effects on skin irritation/corrosion: slightly irritating
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
In accordance with section 1 of REACH Annex XI, the study (required in section 8.1) does not need to be conducted as the study „In vivo skin irritation“ exists.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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