Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Currently viewing:

Administrative data

Description of key information

Additional information

The aerobic biodegradation of hydrocortison was studied in a modified OECD screening test according to test guideline OECD 301E. The test compound was incubated over 28 days at a concentration of 20 mg/L as DOC. Hydrocortioson was degraded to more than 90% at day 28. 60% degradation was reached approximately by day 19, 6 days after start of degradation (10% degradation). The reference compound sodium acetate was degraded to 99% on day 5, the toxicity control did not indicate any inhibiting effect. Thus, hydrocortison is ready biodegradable.