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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: quoted from Atochem 1989, original source not available

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Toxicology Data Summary Sheet
Author:
Atochem North America
Year:
1989
Reference Type:
publication
Title:
Structure Chimique et Activite Pharmacologique de Sels D'amines Tertiaire
Author:
Hazard, R., Cheymal, J., Chabrier. P. and Giudicelli, R.
Year:
1957
Bibliographic source:
Arch. Int. Pharmacodyn. 112 (1957) 36-49

Materials and methods

Test guideline
Guideline:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
2-dimethylaminoethanol
EC Number:
203-542-8
EC Name:
2-dimethylaminoethanol
Cas Number:
108-01-0
Molecular formula:
C4H11NO
IUPAC Name:
2-(dimethylamino)ethanol

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
no data

Administration / exposure

Route of administration:
intravenous
Details on exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 020 mg/kg bw

Applicant's summary and conclusion