Registration Dossier
Registration Dossier
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EC number: 203-677-2 | CAS number: 109-52-4
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study initiation date: 13. October 2009 Study completion date: 02. March 2010
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other:
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Valeric acid
- EC Number:
- 203-677-2
- EC Name:
- Valeric acid
- Cas Number:
- 109-52-4
- Molecular formula:
- C5H10O2
- IUPAC Name:
- pentanoic acid
- Details on test material:
- - Analytical purity (GC): 99,52 % [m/m]
- Purity test date: 11/18/2008
- Source: MV 1065
- Sampling date: 07/22/2007
- Lot/LIMS-ID: 20090825092241
Constituent 1
Results and discussion
- Dissociating properties:
- yes
Dissociation constant
- No.:
- #1
- pKa:
- 4.8
- Temp.:
- 22.5 °C
Applicant's summary and conclusion
- Conclusions:
- The dissociation constant of the test item was determined according to OECD guideline no. 112
[adopted on 12 May 1981] with the titration method.
Dissociation constant (at 22.5 °C): pKA = 4.8
The test(s) used to generate this report was(were) carried out in compliance with the principles of Good Laboratory Practice (GLP) in accordance with the currently valid German Chemical Substance Act (Chemikaliengesetz – ChemG), the underlying Commission Directive 2004/10/EC of 11 February 2004 and the relevant OECD decision of the council on 26 November 1997 and that the results fully reflect those found in the study. - Executive summary:
The dissociation constant of the test item was determined according to OECD guideline no. 112
[adopted on 12 May 1981] with the titration method.
Dissociation constant (at 22.5 °C): pKA = 4.8
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