Registration Dossier
Registration Dossier
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EC number: 248-227-6 | CAS number: 27107-89-7
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis:
The study showed that MOTE at pH 7 and 4 can be considered hydrolytically stable. After 5 days at 50 °C less than 10% MOTE was hydrolyzed (t 0.5 25°C > 1 year).
At pH 9 the 39 % of the untreated substance could be extracted with hexane from the reaction mixture. 61 % degraded into a more water soluble species which could not be unequivocally characterised. It is most likely a hydroxide
Under the simulated gastric conditions (0.1 M HCl / pH 1.2 / 37 °C) MOTE was hydrolyzed to (Monooctyltin chloro bis(2-ethylhexyl mercaptoacetate) (MOTCE2), its monochloro ester.
It can be concluded that MOTCE2 is the only metabolite of MOTE that was formed in the simulated mammalian gastric environment. No Dichloro etster (MOTC2E) or MOTC was formed under the conditions of this study.
Biodegradation
Two guideline studies, investigated the ready biodegradability of the substance are available. Both studies concluded that the substance cannot be considered to be readily biodegradable.
Bioaccumulation:
The substance does not meet the criteria for classification as a bioaccumulative or very bioaccumulative substance as set out by Annex XII of EC Regulation 1907/2008.
Adsorption/desorption:
It is technically not possible to conduct the study as a consequence of the properties of the substance. Therefore, testing is ommitted.
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