Registration Dossier
Registration Dossier
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EC number: 918-139-9 | CAS number: 1228577-90-9
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The substance has very low bioaccumulation potential (predicted log BCF ≤0.5). The bioaccumulation potential of representative components of the UVCB substance was evaluated using three quantitative structure activity relationship (QSAR) models: EPI Suite BCFBAF, OASIS Catalogic and VEGA CAESAR. Model predicted BCF values range from 0.09 to 3.16 (or logBCF values range from -1.02 to 0.50) for those three representative components. The logPow values for potential biodegradation products predicted using QSAR models were all ≤3 indicating that potential degradants also have low bioaccumulation potential. Considering that the substance has low log Pow (log Pow ≤3) and has very low predicted bioaccumulation potential (predicted log BCF ≤0.5), a laboratory bioaccumulation study is waived.
Key value for chemical safety assessment
- BCF (aquatic species):
- 3.16 L/kg ww
Additional information
In accordance with Column 2 of REACH Annex IX, the study does not need to be conducted as the substance can be expected to have a low potential for bioaccumulation (log Pow ≤3)
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