Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 904-693-9 | CAS number: -
Endpoint summary
Administrative data
Description of key information
According to R.7.10.1 (ECHA, R 7c, 2017) and the Integrated Testing Strategy (ITS, Figure R.7.10-1, ECHA guidance R.7.c), all available information should be assessed before further testing for bioaccumulation is done. The available information with regards to bioaccumulation for the substance is a measured average log Kow of 4.4. This log Kow is sufficient for the B in the PBT-assessment, classification and labelling and the chemical safety assessment. The log Kow does not indicat a B concern or the PBT assessment, as the value is below the cut-off value of 4.5 used for screening. This log Kow does not result in environmental classification based on available aquatic toxicity data. For the chemical safety assessment, a predicted BCF of 1100 L/kg ww. (calculated in EUSES with the Veith relationship based on the measured log Kow) is sufficient to fulfill the data gap. Therefore, the available information is deemed sufficient and therefore no further bioaccumulation testing is required.
The BCFs for terrestrial organisms were calculated using QSARs of Jager (1998), incorporated in the EUSES model, and yielded a values of 302 L/kg ww using a log Kow of 4.4.
It can be anticipated that simple esters, such as acetic esters, will be converted to the respective alcohols and therefore the BCF values calculated are considered worst case values.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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