Registration Dossier
Registration Dossier
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EC number: 225-878-4 | CAS number: 5131-66-8
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Propylene glycol butyl ether does not have PBT or vPvB Properties.
Propylene glycol butyl ether meets the criteria for ready biodegradation, according to the results in the 301E modified OECD screening test showing 90% degradation within the 10-day window. This data is supported by more than 60% degradation of PnB observed in the Closed Bottle Test and the Modified Sturm Test. In conclusion, propylene glycol butyl ether can be considered as readily biodegradable under aerobic conditions.
Propylene glycol butyl ether has a low log Kow (log Kow = 1.2) and is readily biodegradable, which indicates that propylene glycol butyl ether offers little potential for bioconcentration in aquatic organisms.
Measured aquatic toxicity data indicate that propylene glycol butyl ether presents a low toxicity hazard to aquatic species. All EC50/LC50 values (fish, daphnia and algae) are greater than 500 mg/l.
Propylene glycol butyl ether is not classified as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) and there is no evidence of chronic toxicity, as identified by the classifications STOT (repeated exposure), category 1 (oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) or category 2 (oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) according to Regulation (EC) No 1272/2008.
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