Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Reliable acute toxicity tests results are available for freshwater fish (Brachydanio rerio), invertebrates (Daphnia magna) and algae (Scenedesmus subspicatus). LL50 or EL50 values for the three organisms were >1000, <1 and >500 mg/l respectively. A NOELR of 32 mg/l was determined in the algal test. The LL50, EL50 and NOELR values all exceed the solubility of the substance (0.01 mg/l predicted). It is likely that the Daphnia magna and (in a read-across test) algae were subject to physical effects of undissolved test substance (or precipitated cross-linked oligomers of the silanol) and the results of these tests therefore need to be treated with caution. The substance itself appears to be non-toxic at the solubility limit; this interpretation is supported by QSAR, which predicts that no short-term or long-term ecotoxic effects would be expressed in fish, invertebrates or algae in either short or long term tests at the limit of solubility of the substance.

However, based on read-across from 211519-85-6, the hydrolysis product may have non-classifiable effects, though physical effects caused by undissolved material and precipitated siloxanes may have contributed. In view of the properties of the registration substance, the chemical safety assessment focuses on the parent form, however it is necessary to derive an indicative PNEC in order to assess risk.