Registration Dossier

Administrative data

Endpoint:
toxicity to terrestrial plants: short-term
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Supporting study to get an impression of the effects on terrestrial organisms

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Unnamed
Year:
1977
Reference Type:
publication
Title:
Unnamed
Year:
1975

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Name of test material (as cited in study report): Acetaldehyde

Sampling and analysis

Analytical monitoring:
no

Test substrate

Vehicle:
not specified

Test organisms

Species:
Lactuca sativa
Plant group:
Dicotyledonae (dicots)
Details on test organisms:
- Common name: Lettuce
- Plant family: Asteraceae
- Variety: Great Lakes
- Source of seed: Sutton and Son Ltd.

Study design

Test type:
seed germination/root elongation toxicity test
Study type:
laboratory study
Substrate type:
other: 0.5 per cent agar solution
Total exposure duration:
3 d

Results and discussion

Effect concentrationsopen allclose all
Species:
Lactuca sativa
Duration:
3 d
Dose descriptor:
EC50
Effect conc.:
22.1 other: mmol
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
germination
Remarks on result:
other: confidence limit +/- 1.2 mmol. Original values as cited in the article.
Species:
Lactuca sativa
Duration:
3 d
Dose descriptor:
EC50
Effect conc.:
972.4 other: mg
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
germination
Remarks on result:
other: confidence limit +/- 52.8 mg. Converted value from mmol to mg

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
Based on the results, the EC50 of of acetaldehyde based on the inhibition of germination of Lactuca sativa was 22.1 mmol, corresponding to 972.4 mg.
Executive summary:

The effects of seed germination inhibition of acetaldehyde was investigated in a laboratory test. Twenty lettuce seeds were exposed to acetaldehyde in agar medium at a constant test temperature of 30°C. Inhibition of germination was determined three days after test start. Based on the observed effects, the EC50 of acetaldehyde was calcuolated to be 22.1 mmol, corresponding to 972.4 mg.