Registration Dossier
Registration Dossier
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EC number: 939-464-2 | CAS number: 121617-08-1
Endpoint summary
Administrative data
Description of key information
Additional information
Acute tests on all three trophic levels were performed to examine the acute aquatic toxicity of LAS-TEA. Additionally, a chronic test on aquatic invertebrates and algae is available.
Brachydanio rerio was the most sensitive species in the acute toxicity tests with a 96-h LC50 of 5.7 mg/L. Daphnia magna was the most sensitive species in the long-term toxicity tests with a reproduction 21-d NOEC of 2.8 mg/L.
Depending on the outcome of the chemical safety asssessment long-term testing on fish may need to be proposed, but sufficient data are available for LAS-Na and TEA, which provide adequate toxicity data for the long-term toxicity to fish (see read-across statement).
On the basis of the available tests LAS-TEA does not need to be classified as acutely harmful for aquatic organisms.
The toxicity of LAS-TEA to aquatic organisms may be described by the toxicity of LAS-Na and TEA according to the read-across statement in which full dissociation of the LAS-TEA in water is supported.
For LAS-Na a large number of aquatic toxicity studies are available. The EC50s and NOECs are in the same order of magnitude as those found for LAS-TEA but slightly lower. The EC50s and NOECs found in toxicity tests with TEA are higher. Therefore, a precautionary approach is taken for the derivation of the PNECaqua. The large body of long-term ecotoxicity data for LAS-Na results in a precautionary estimate of the PNECaqua for the read-across analogue LAS-TEA.
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