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EC number: 700-990-0
CAS number: -
Reproduction/developmental toxicity screening test (equivalent to OECD 422, GLP)- Parental and developmental NOAEL: 1000 mg/kg bw/dayPrenatal developmental toxicity study (equivalent to OECD 414, GLP)- Maternal and developmental NOAEL: 1000 mg/kg bw/day
A NOAEL of 1000 mg/kg bw/day for developmental toxicity was established
in the two available key studies and was based on the absence of adverse
effects. The NOAEL was supported by two additional studies: one study
was the pilot study for the other, a prenatal developmental toxicity
study. Both studies established a NOAEL of 1000 mg/kg bw/day as well,
based on the absence of adverse effects up to the highest dose tested.
Based on the NOAEL of 1000 mg/kg bw/day that was established and the
criteria outlined in Annex I of 1272/2008/EC and Annex VI of 67/548/EEC,
t-BuTPP does not need to be classified for repro- or developmental
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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