Registration Dossier
Registration Dossier
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EC number: 202-597-5 | CAS number: 97-63-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acute fish: 96 hr LC50 100 mg/L Salmo gairdneri (new name: Oncorhynchus mykiss)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
For ethyl methacrylate the study in Onchorynchus mykiss showed a 96 -hr LC50 of 100 mg/L. Data are available for the lower alkyl methacrylates category which indicate a trend of increasing toxicity (96 h LC50) from the acid and the methyl ester to the ester with the longest side chain in the category, 2‑EHMA. See the following table:
Summary of short-term effects on fish
Ester |
Fish Species |
LC50(mg/l) |
Exposure time |
Study Type |
Remarks |
Reference |
MAA |
Rainbow Trout (Oncorhynchus mykiss) |
85b |
96 h |
EPA guideline 660/ 3-75-009a |
Rel. 1 |
Bowman, 1990a |
MMA |
Rainbow Trout (Oncorhynchus mykiss) |
>79b |
96 h |
EPA guideline 660/ 3-75-009a |
Rel. 1 |
Bowman, 1990b |
EMA |
Rainbow Trout (Oncorhynchus mykiss) |
100b, c |
96 h |
OECD 203 (flow-through) |
Rel. 1 |
Sousa, 1995a |
i-BMA |
Rainbow Trout (Oncorhynchus mykiss) |
20b, c |
96 h |
OECD 203 (flow-through) |
Rel. 1 |
Sousa, 1995b |
n-BMA |
Fathead Minnow (Pimephales promelas) |
11b |
96 h |
OECD 203 (flow-through) |
Rel. 2 |
Morris, 1993 |
n-BMA |
Medaka |
5.57b, c
|
96 h |
OECD 203 (semi-static 24 h) |
Rel. 1 |
MoE, 1998a |
2-EHMA |
Medaka |
2.78b, c, d) |
96 h |
OECD 203 (semi-static 24 h) |
Rel. 2 |
MoE, 1998b |
aequivalent to OECD 203;bbased on measured concentrations;cdispersant used;dmost test concentrations were above the limit of solubility.
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