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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Adequacy of study:
other information
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
publication
Title:
Human and rat|mononuclear cell proliferation show different sensitivity, in vitro, to single constituents of dental composite resins.
Author:
Aronsson G, Dahlgren UI, Karlsson S
Year:
2000
Bibliographic source:
J. Biomed. Mater. Res. 53(6): 651 - 657

Materials and methods

Type of study / information:
Type: Cell proliferation in vitro

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Specific details on test material used for the study:
Purity: no data

Results and discussion

Any other information on results incl. tables

Results:
ID50: 5 umol/L
The concentration at which the proliferation rate was reduced by 50% (ID50-value), was graphhhhhically obtained
from individual dose vs. response curves. As the counts per
min (cpm) varied ammong experiments, the graphs were
constructed with data  expressed as percent of the control
containing 0.1 % ethanol (control = 100 %). The inhibition rank order
is based on the median value of the ID50 values for each
substance.

Applicant's summary and conclusion