Registration Dossier
Registration Dossier
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EC number: 201-939-0 | CAS number: 89-78-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Report to RIFM, February 16, 1973
- Author:
- Opdyke DLJ
- Year:
- 1 976
- Bibliographic source:
- Levenstein I; Report to RIFM, February 16, 1973: cited in Opdyke, D.L.J.: Fd Cosmet. Toxicol. 14, 473-474 (1976)
Materials and methods
- Principles of method if other than guideline:
- acute dermal toxicity was tested
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- Menthol
- EC Number:
- 201-939-0
- EC Name:
- Menthol
- Cas Number:
- 89-78-1
- Molecular formula:
- C10H20O
- IUPAC Name:
- 2-isopropyl-5-methylcyclohexanol
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- no data
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
Any other information on results incl. tables
no data
Applicant's summary and conclusion
- Executive summary:
In rabbits the acute dermal LD50 exceeded 5000 mg/kg bw
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