Registration Dossier
Registration Dossier
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EC number: 203-809-9 | CAS number: 110-86-1
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- no data
- Type of information:
- other: handbook
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This is a reliable textbook of toxicology. No information on methods used to generate data.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Heterocyclic and Miscellaneous Nitrogen Compounds. pp. 2719-2727
- Author:
- Reinhardt, C.F.
- Year:
- 1 981
- Bibliographic source:
- Patty's Industrial Hygiene and Toxicology, 3rd revised edition, Clayton, G.D. And F.E. Clayton, eds. J. Wiley & Sons, New York, NY U.S.
Materials and methods
- Principles of method if other than guideline:
- No information on methods used. As this is older, most likely this is an in vivo method using guinea pigs.
- GLP compliance:
- not specified
- Type of study:
- not specified
Test material
- Reference substance name:
- Pyridine
- EC Number:
- 203-809-9
- EC Name:
- Pyridine
- Cas Number:
- 110-86-1
- Molecular formula:
- C5H5N
- IUPAC Name:
- pyridine
Constituent 1
Results and discussion
In vivo (non-LLNA)
Results
- Clinical observations:
- Not sensitising
- Remarks on result:
- other: Clinical observations: Not sensitising.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information based on professional judgement
- Conclusions:
- Pyridine was reported by a reliable toxicology text to be non-sensitising.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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