Registration Dossier

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Remarks:
Secondary source, original report not available
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Reference Type:
other: internal communication
Title:
Unnamed
Year:
1995
Report date:
1995

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
3,5,5-trimethylhexanoic acid
EC Number:
221-975-0
EC Name:
3,5,5-trimethylhexanoic acid
Cas Number:
3302-10-1
Molecular formula:
C9H18O2
IUPAC Name:
3,5,5-trimethylhexanoic acid
Details on test material:
CAS No. 3302-10-1, not further specified

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Details on study design:
no data

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
The acute dermal toxicity was low (> 2000 mg/kg bw). No conclusions can be drawn due to the lack of experimental details reported in the secondary source.
Executive summary:

A secondary source reports a dermal LD50 value > 2000 mg/kg bw. The original report is not available (Exxon, undated, as cited in Hoechst AG, 1995).

Categories Display