Registration Dossier

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
general observations
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Patty's Toxicology
Author:
Bingham, E.; Cohrssen, B.; Powell, C.H
Year:
2001
Bibliographic source:
Volumes 1-9 5th; p. V4 1294; ed. John Wiley & Sons

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

In vivo

Results
Remarks on result:
probability of severe irritation

Applicant's summary and conclusion

Interpretation of results:
Category 1B (corrosive) based on GHS criteria
Conclusions:
Methylhydrazine can produce severe skin and eye damage in animal models and would be expected to perform similarly in humans.
Executive summary:

Methylhydrazine can produce severe skin and eye damage in animal models and would be expected to perform similarly in humans.