Registration Dossier
Registration Dossier
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EC number: 309-798-8 | CAS number: 101012-97-9
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented study report, which meets basic scientific principles
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 970
- Report date:
- 1970
Materials and methods
- Principles of method if other than guideline:
- BASF test
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- Tridecanamine, N-tridecyl-, branched and linear
- EC Number:
- 309-798-8
- EC Name:
- Tridecanamine, N-tridecyl-, branched and linear
- Cas Number:
- 101012-97-9
- Molecular formula:
- C24 H50 NH - C28 H58 NH
- IUPAC Name:
- (2-methyldodecyl)(tridecyl)amine; ditridecylamine
- Details on test material:
- - Name of test material (as cited in study report): Ditridecylamin techn., Isomerengemisch
- Physical state: liquid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: Kisslegg
- Sex:
- male/female
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- other: 0.1 - 30% emulsion with traganth
- Doses:
- 12.5, 16, 20, 25, 100, 200, 1600 mm³/kg
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
- Details on study design:
- - Duration of observation period following administration: 14 days
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs, body weight, histopathology
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- ca. 10 mg/kg bw
- Remarks on result:
- other: Original data: 13 mm³/kg
- Mortality:
- All animals died at the concentrations of 16 mm³/kg and higher (equivalent to a concentration of ca. 12.3 mg/kg). At 12.5 mm³/kg (equivalent to a concentration of ca. 9.6 mg/kg) none of the males died compared to 3 of the females.
- Clinical signs:
- Dyspnea, staggering, atony, apathy and slight twitching
- Gross pathology:
- Sporadically, adhesions in the upper abdomen
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
