Benzaldehyde, 2-hydroxy-5-nonyl-, oxime, branched

Adsorption / desorption

Link to relevant study record(s)

Reference

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

09 - 12 Jun 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

Deviations:

no

GLP compliance:

yes

Type of method:

HPLC estimation method

Media:

soil/sewage sludge

Specific details on test material used for the study:

- Name of test material (as cited in study report): C-SAT 090069
- Physical state: amber coulored liquid
- Analytical purity: > 89%
- Lot/batch No.: C-081

Radiolabelling:

no

Test temperature:

25°C

Details on study design: HPLC method:

EQUIPMENT
- Apparatus: HPLC autosampler and pump, Waters 2695
- Type, material and dimension of analytical (guard) column: Lichrospher 100 CN, 250/4 mm, 5 µm
- Detection system: PDA detector, Waters 996

MOBILE PHASES
- Type: 55% methanol / 45% aqueous buffer solution (0.01 M citric acid at pH 6.0) (v/v)
- Experiments with additives carried out on separate columns: no

DETERMINATION OF DEAD TIME
- Method: by means of homologous series / by inert substances which are not retained by the column

REFERENCE SUBSTANCES
- Identity: Sodium nitrate, acetanilide, phenol, methyl benzoate, naphthalene, 1,2,3-trichlorobenzene, phenanthrene, basic blue 41

DETERMINATION OF RETENTION TIMES
- Quantity of test substance introduced in the column: 0.00223 - 0.00442 mg
- Quantity of reference substances: 0.0035 - 0.0050 mg

REPETITIONS
- Number of determinations: 3

EVALUATION
- Calculation of capacity factors k': = (tr-to) + to

Analytical monitoring:

yes

Key result

Type:

log Koc

Value:

3.7

Temp.:

25 °C

Details on results (HPLC method):

- Retention times of reference substances used for calibration: sodium nitrate: 1.979, acetanilide: 3.226, phenol: 3.254, methyl benzoate: 3.759, naphthalene: 5.653, 1,2,3-trichlorobenzene: 5.619, phenanthrene: 9.042, basic blue 41: 13.196
- Details of fitted regression line (log k' vs. log Koc): y = 3.783x + 1.994 (with x = log k' and y = log Koc); R = 0.996
- Average retention data for test substance: 7.59

Validity criteria fulfilled:

yes

Conclusions:

In a study according to OECD test guideline 121 under GLP, the adsorption coefficient log Koc of the registered substance is 3.7.

Executive summary:

The adsorption coefficient log K_oc of the registered substance was estimated according to OECD Guideline for the testing of chemicals No. 121 to be log Koc = 3.7.

Description of key information

Adsorption is expected based on a measured log Koc value of 3.7 (OECD 121)

Key value for chemical safety assessment

Koc at 20 °C:

5 011.9

Additional information

One study investigating the adsorption potential of Benzaldehyde, 2-hydroxy-5-nonyl, oxime, branched (CAS 174333-80-3) is available. The study was performed according to GLP and OECD guideline 121 (Frischmann 2010). The log Koc value at 25 °C is determined to be 3.7 (Koc = 5011.9). This value indicate that the substance exhibit potential for adsorption to organic soil and sediment particles.

[LogKoc: 3.7]