Registration Dossier
Registration Dossier
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EC number: 222-182-2 | CAS number: 3380-34-5
Bioaccumulation: terrestrial
Administrative data
Link to relevant study record(s)
Description of key information
Potential for bioaccumulationin earthworms is low.
Key value for chemical safety assessment
Additional information
A bioaccumulation study in earthworm was performed according to a draft OECD guideline (adopted as OECD 317, 2010). Test material was radio-labeled (13C). Test concentrations were 01. and 1.0 µg/g (nominal) and were analytically verified. In addition a control and a solvent (acetone) control were run. The uptake and the depuration phase were each 21 d. The following BAF values were determined (normalised to lipid fraction):
- BAF steady state: 52.1 at 0.1 µg/g, 31.3 at 1.0 µg/g
- BAF kinetic: 0.59 at 0.1µg/g, 1.4 at 1.0 µg/g
Elimination was observed during the 21 -d depuration phase.
Considering the similarity in the Koc and Kow values and the predominance of the unionized parent compound in the terrestrial environment, the potential for bioaccumulation in the earthworm based on present knowledge is low.
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