Registration Dossier
Registration Dossier
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EC number: 202-870-9 | CAS number: 100-61-8
Endpoint summary
Administrative data
Description of key information
Acute oral
LD50 male rats = 782 mg/kg bw
LD50 female rats= 716 mg/kg bw
Acute inhalation
Induction of 5% MetHb formation in dogs = 165 mg/m3 air
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 716 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- discriminating conc.
- Value:
- 165 mg/m³ air
Additional information
The test substance -like aniline- is readily absorbed irrespective the route of administration. Further, the symptoms and effects observed are similar for all routes of administration and identical to those observed after acute exposure to aniline.
Justification for classification or non-classification
Based on the fact that the test substance is toxic irrespective the route of administration it is justified that the current classification includes "acute toxic" for all three routes.
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