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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD's Guidelines for Testing of Chemicals No. 203 " Fish Acute Toxictiy Test"(19992), SEPA, P.R. China the Guidelines for Testing of Chemicals No. 203 "Fish, Acute Toxicity Test"(May 2004)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h

Test conditions

Hardness:
10-250mg/L CaCO3
Test temperature:
23+/-deg.C
pH:
6-8.5
Nominal and measured concentrations:
1.0, 1.8, 3.2, 5.6, and 10 mg/L
Reference substance (positive control):
yes

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
6.73 mg/L
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
3.21 mg/L
Details on results:
During the 96-hr exposure period, the fish treated with the test concentration at 5.6 mg/L (geometric mean determined concentration is 5.82 mg/L) and higher concentrations showed visible toxic signs, e.g., lethargy, slowly swimming, and loss of equilibrium. The "no observed effect concentration" was 3.2 mg/L (geometric mean determined concentration is 3.21 mg/L).

Applicant's summary and conclusion

Conclusions:
Based on the fish toxicity grading criteria in the Guidelines for the Hazard Evaluation of New Chemical Substances, Environmental Protection Agency of P.R.C. (HJ/T 154-2004), the test substance is graded as a chemical with extremely high toxicity (2) fish under the experiement conditions of this study.
Executive summary:

Based on the fish toxicity grading criteria in the Guidelines for the Hazard Evaluation of New Chemical Substances, Environmental Protection Agency of P.R.C. (HJ/T 154-2004), the test substance is graded as a chemical with extremely high toxicity (2) fish under the experiement conditions of this study.