Registration Dossier
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EC number: 500-195-7 | CAS number: 68131-39-5 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In the key study an EC50 for Daphnia magna of 0.14 mg/L. could be determined after 48 h of exposure.
Nevertheless that endpoint is not used for PNEC-calculation as PNEC-values were calculated on the basis of a HC5-approach.
Key value for chemical safety assessment
Additional information
For alcohol C12 -15 ethoxylates three reliable studies are avialable. In the GLP-study of Seaber (Croda, 1994) an EC50 of 0.23 mg/L (nominal; purity of test material: not stated) was determined for the alcohol ethoxylate mixture C12 - C15 with a degree of ethoxylation of 3 after 48 h of exposure. The test was conducted according to OECD 202. The second reliable test for alcohol C12 - C15 ethoxylates with 3EO is not conducted according to a recommended guideline but with a method comparable to current standards. In that non-GLP study an EC50-value of 0.14 mg/L is reported for daphnids after a 48 h test period. The third reliable test available is conducted with alcohol C12 -15 ethoxylates branched and linear (CAS 106232 -83 -1) according to OECD 202 (Consonni, Sasol, 2003). The test resulted in an EC50 -value > 2 mg/L after 48 h of exposure. The study of Stephenson (Shell, 1982) which reported an EC50 of 0.14 mg/L is determined as key study.
In addition to tests conducted on daphnids, a GLP-study is available for marine invertebrates. The study is conducted according to the PARACOM ring test protocol and reported an EC50 -value for Acartia tonsa of 0.88 mg/L (Bogers, Shell, 1993). This result is in line with the results given for daphnids.
In addition to the described data, three abstracts of studies are available which are not sufficient for evaluation as only short abstracts are available. Generally the EC50 -values mentioned in the abstracts are in line with the described endpoints given in the reliable studies and were thus listed as supporting data.
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