Registration Dossier
Registration Dossier
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EC number: 500-281-4 | CAS number: 98362-33-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
A Respiration Inhibition Test with activated sludge according to OECD Guideline No. 209 was carried out with the test item 2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid. Test system was activated sludge of a municipal treatment plant. The test was carried out under static conditions with the substance concentrations of 560 - 750 - 1000 mg/L in a geometrical series with a dilution factor of 1.33. The respiration rates of the control, reference and test item replicates were measured after a contact time of three hours, and the inhibitory effects of the test and reference item were determined in comparison to the control respiration rates. The mean inhibition of respiration for the test item replicates ranged from 5 % to 7 %. In order to check the activity of the test system and the test conditions a reference test was carried out with copper (II) sulphate pentahydrate as reference item and the reference toxicity was determined. The EC50-value for the reference item was 99.1 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
The NOEC of the test item 2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid is 1000 mg/L, the EC50 of the test item is > 1000 mg/L. The test item is not toxic up to the concentration of 1000 mg/L, to activated sludge of a municipal sewage treatment plant.
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