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EC number: 232-092-5
CAS number: 7786-17-6
Table 1 Summary of
No. of Rats
Average Bodyweight* (g)
(No. of rats exhibiting symptom)
Number of Deaths
show the average initial weights of the survivors.
†This value was not
legible in the original study report. However the value was easily
inferred from the percentage mortality figure.
A = abdominal pain
E = excessive laxation
U = urinary incontinence
P = prostration
An acute oral study was carried out to access the toxic potential of the
test material, broadly in accordance with OECD guideline 401.
The test material was administered as a 50 percent solution in
cottonseed oil to groups of young adult albino rats at dose levels of
16.38, 22.62 and 32.72 g/kg bw (with ten animals per sex per dose). The
animals were observed for 14 days before being subjected to necropsy.
Whilst some mortality was seen, it did not increase in proportion to the
dosage. Clinical signs exhibited by all animals were abdominal pain,
excessive laxation and urinary incontinence.
No gross evidence of pathology was seen at necropsy among the survivors
sacrificed after 14 days. In the examination of those that died
throughout the observation period, the gastric mucosa was observed to be
Under the conditions of this study, the LD50 value was greater than 32.7
g/kg bw. The test material is not classified in accordance with EU
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