Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Data is from Alfa-Aesar MSDS
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,2-trifluoroacetamide
EC Number:
206-559-9
EC Name:
2,2,2-trifluoroacetamide
Cas Number:
354-38-1
Molecular formula:
C2H2F3NO
IUPAC Name:
2,2,2-trifluoroacetamide
Details on test material:
- Name of test material : 2,2,2-trifluoroacetamide
- Molecular formula : C2H2F3NO
- Substance type: Organic
- Physical state: Solid

Test animals

Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Remarks on result:
other: Irritant for skin

Applicant's summary and conclusion

Interpretation of results:
irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
According to Alfa-Aesar MSDS 2,2,2-trifluoroacetamide was found to be irritating to skin and mucous membrane.
Executive summary:

According to Alfa-Aesar MSDS 2,2,2-trifluoroacetamide was found to be irritating to skin and mucous membrane.