Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25.10.2012 to 06.11.2012
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Measurement of capacity of a compound to dissociate into respective ions.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
- Name of test material : 2,2,2-trifluoroacetamide
- Molecular formula : C2H2F3NO
- Substance type: Organic
- Physical state: Solid

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
0
Temp.:
23 °C
No.:
#2
pKa:
0
Temp.:
23 °C
No.:
#3
pKa:
0
Temp.:
23 °C

Applicant's summary and conclusion

Conclusions:
The average experimental pKa value for 2,2,2-trifluoroacetamide was found to be 0.000000004 at 23 deg C indicating that it has dissociating properties.
Executive summary:

The average experimental pKa value for 2,2,2-trifluoroacetamide was found to be 0.000000004 at 23 deg C indicating that it has dissociating properties.