Registration Dossier
Registration Dossier
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EC number: 500-201-8 | CAS number: 68213-23-0 1 - 2.5 moles ethoxylated
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In the key study an EC50 for Daphnia magna of 2.7 mg/L. could be determined after 48 h of exposure.
Nevertheless that endpoint is not used for PNEC-calculation as PNEC-values were calculated on the basis of a HC5-approach.
Key value for chemical safety assessment
Additional information
A GLP-study on aquatic invertebrates (Daphnia magna) in static systems is available. In the key-study of Stelter (1995) according to the EU-guideline 92/69/EWG, with alcohol ethoxylates of a chain length of C12 - C13 and a degree of ethoxylation of 9 an EC50 of 2.7 mg/L (purity of test material: 100%) was determined. In addition read-across to a supporting study conducted with C12 -14 alcohol ethoxylates (CAS 68439 -50 -9) is prepared as the tested alcohol C12 -18 ethoxylate is highly ethoxylated (9EO) and thus might be of lower toxicity as lower ethoxylated mixtures. In the study of Scholz (Sasol, 1993) on alcohol ethoxylates with a chain length of C12 - C14 and a degree of ethoxylation of 2 an EC50 of 0.53 mg/L (corresponding to 0.39 mg a.s./L based on the content of active substance in the test substance: 73% w/w) was determined. Regarding the composition of both mixtures for the alcohol C12 -18 ethoxylates even a lower toxicity is expected as for the C12 -14 mixture. Thus the toxicity of alcohol C12 -18 ethoxylates is expected to be between 0.39 mg a.s./L and 2.7 mg/L.
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